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SC 57461
CAS No. 423169-68-0
SC 57461 ( SC 57461A )
产品货号. M14440 CAS No. 423169-68-0
A potent and selective inhibitor of LTA4 hydrolase (LTA4H) with IC50/Ki of 5 nM/23 nM; inhibits calcium ionophore-induced LTB(4) production in human whole blood (IC50=49 nM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥786 | 有现货 |
|
| 10MG | ￥1256 | 有现货 |
|
| 25MG | ￥2535 | 有现货 |
|
| 50MG | ￥3993 | 有现货 |
|
| 100MG | ￥5856 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称SC 57461
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A potent and selective inhibitor of LTA4 hydrolase (LTA4H) with IC50/Ki of 5 nM/23 nM; inhibits calcium ionophore-induced LTB(4) production in human whole blood (IC50=49 nM).
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产品描述A potent and selective inhibitor of LTA4 hydrolase (LTA4H) with IC50/Ki of 5 nM/23 nM; inhibits calcium ionophore-induced LTB(4) production in human whole blood (IC50=49 nM), no effect on production of the cyclooxygenase metabolite thromboxane B(2); orally active in vivo.Irritable Bowel Syndrome Discontinued
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同义词SC 57461A
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通路Others
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靶点Other Targets
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受体Other Targets
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研究领域Other Indications
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适应症Irritable Bowel Syndrome
化学信息
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CAS Number423169-68-0
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分子量363.88
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分子式C20H25NO3.HCl
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C(O)CCN(C)CCCOC1=CC=C(CC2=CC=CC=C2)C=C1
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化学全称3-((3-(4-benzylphenoxy)propyl)(methyl)amino)propanoic acid hydrochloride
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Askonas LJ, et al. J Pharmacol Exp Ther. 2002 Feb;300(2):577-82.
2. Kachur JF, et al. J Pharmacol Exp Ther. 2002 Feb;300(2):583-7.
3. Penning TD, et al. J Med Chem. 2002 Aug 1;45(16):3482-90.
2. Kachur JF, et al. J Pharmacol Exp Ther. 2002 Feb;300(2):583-7.
3. Penning TD, et al. J Med Chem. 2002 Aug 1;45(16):3482-90.
产品手册
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